RNA interference therapeutics for cancer: challenges and opportunities

RNA interference therapeutics for cancer: challenges and opportunities

Abstract. RNA interference (RNAi) is a sequence-specific, post-transcriptional gene silencing mechanism in animals and plants, which is mediated by double-stranded RNA (dsRNA). There has recently been an increasing interest in harnessing the gene silencing activity of dsRNA to develop novel drugs fo...

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Bibliographic Details
Main Authors: Bora, R., Gupta, D., Mukkur, Trilochan, Saini, K.
Format: Journal Article
Published: Spandidos Publications 2012
Subjects:
target specificity
short interfering RNA
short interfering RNA delivery
gene silencing
cancer
RNA interference
Online Access:http://www.spandidos-publications.com/mmr/6/1/9
http://hdl.handle.net/20.500.11937/49685

Internet

http://www.spandidos-publications.com/mmr/6/1/9
http://hdl.handle.net/20.500.11937/49685

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