Construction and preliminary immunobiological characterization of a novel, non-reverting, intranasal live attenuated whooping cough vaccine candidate
We describe the construction and immunobiological properties of a novel whooping cough vaccine candidate, in which the aroQ gene, encoding 3-dehydroquinase, wasdeleted by insertional inactivation using the kanamycin resistance gene cassette and allelic exchange using a Bordetella suicide vector. The...
| Main Authors: | , , |
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| Format: | Journal Article |
| Published: |
Han'gug Mi'saengmul Saengmyeong Gong Haghoe
2012
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| Online Access: | http://www.jmb.or.kr/ http://hdl.handle.net/20.500.11937/49611 |