Molecular dynamics simulations of ligand-induced backbone conformational changes in the binding site of the periplasmic lysine-, arginine-, ornithine-binding protein

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Molecular dynamics simulations of ligand-induced backbone conformational changes in the binding site of the periplasmic lysine-, arginine-, ornithine-binding protein

The periplasmic lysine-, arginine-, ornithine-binding protein (LAOBP) traps its ligands by a large hinge bending movement between two globular domains. The overall geometry of the binding site remains largely unchanged between the open (unliganded) and closed (liganded) forms, with only a small numb...

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Bibliographic Details
Main Authors:	Yang, A., Mancera, Ricardo
Format:	Journal Article
Published:	Kluwer Academic Publishers 2008
Online Access:	http://hdl.handle.net/20.500.11937/4951

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