Molecular dynamics simulations of ligand-induced backbone conformational changes in the binding site of the periplasmic lysine-, arginine-, ornithine-binding protein
The periplasmic lysine-, arginine-, ornithine-binding protein (LAOBP) traps its ligands by a large hinge bending movement between two globular domains. The overall geometry of the binding site remains largely unchanged between the open (unliganded) and closed (liganded) forms, with only a small numb...
| Main Authors: | , |
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| Format: | Journal Article |
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Kluwer Academic Publishers
2008
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| Online Access: | http://hdl.handle.net/20.500.11937/4951 |