Structural Investigation of MscL Gating Using Experimental Data and Coarse Grained MD Simulations

QR Code

Structural Investigation of MscL Gating Using Experimental Data and Coarse Grained MD Simulations

The mechanosensitive channel of large conductance (MscL) has become a model system in which to understand mechanosensation, a process involved in osmoregulation and many other physiological functions. While a high resolution closed state structure is available, details of the open structure and the...

Full description

Bibliographic Details
Main Authors:	Deplazes, Evelyne, Louhivuori, M., Jayatilaka, D., Marrink, S., Corry, B.
Format:	Journal Article
Published:	2012
Online Access:	http://hdl.handle.net/20.500.11937/4858

Similar Items

Differential effects of lipids and lyso-lipids on the mechanosensitivity of the mechanosensitive channels MscL and MscS
by: Nomura, T., et al.
Published: (2012)

Testing the use of molecular dynamics to simulate fluorophore motions and FRET
by: Deplazes, Evelyne, et al.
Published: (2011)

ExiFRET: Flexible tool for understanding FRET in complex geometries
by: Deplazes, Evelyne, et al.
Published: (2012)

Optimization of Coarse-Grained Interaction Potential: Inside Inherent Limitations of Coarse-Graining Methods
by: Kowalczyk, Piotr, et al.
Published: (2011)

Molecular simulations of venom peptide-membrane interactions: Progress and challenges
by: Deplazes, Evelyne
Published: (2018)

Membrane-binding properties of gating modifier and pore-blocking toxins: Membrane interaction is not a prerequisite for modification of channel gating
by: Deplazes, Evelyne, et al.
Published: (2016)

Comparing the Ability of Enhanced Sampling Molecular Dynamics Methods to Reproduce the Behavior of Fluorescent Labels on Proteins
by: Walczewska-Szewc, K., et al.
Published: (2015)

Intra-swash hydrodynamics and sediment flux for dambreak swash on coarse-grained beaches
by: O'Donoghue, Tom, et al.
Published: (2016)

Role of Short-Range Directional Interactions in Coarse-Graining of Protic/Aprotic Liquids
by: Kowalczyk, Piotr, et al.
Published: (2009)

Coarse-graining and renormalisation group methods for the elucidation of the kinetics of complex nucleation and growth processes
by: Coveney, Peter V., et al.
Published: (2006)

The effect of temperature and pressure on the self-assembly of dipalmitoylphosphatidylcholine using coarse-grained molecular dynamics
by: Shaari, Nurul Syahidah, et al.
Published: (2014)

Interaction of monomeric Ebola VP40 protein with a plasma membrane: a coarse-grained molecular dynamics (CGMD) simulation study
by: Mohamad Yusoff, Mohamad Ariff, et al.
Published: (2018)

Experimental study on the properties of local coarse aggregate in Sarawak
by: Chong, Huey Ching
Published: (2006)

MSc Entrepreneurship
by: Jones, Andrew
Published: (2009)

Coarse grid simulation of gas-solid flows in riser
by: Shah, Milinkumar T.
Published: (2011)

A coarse-grained molecular dynamics study of DLPC, DMPC, DPPC, and DSPC mixtures in aqueous solution
by: Karjiban, Roghayeh Abedi, et al.
Published: (2013)

Data driven grain profitability through “on-farm experimentation”
by: Easton, Julia, et al.
Published: (2022)

Macroscopic coherent structures in a stochastic neural network: from interface dynamics to coarse-grained bifurcation analysis
by: Avitable, Daniele, et al.
Published: (2017)

Sense of community in gated and non-gated residential / Siti Rasidah Md Sakip, Noraini Johari and Mohd Najib Mohd Salleh.
by: Md Sakip, Siti Rasidah, et al.
Published: (2018)

PM : Mantapkan MSC
Published: (2009)

Penjenamaan MSC Malaysia
Published: (2008)

MSc Counselling Fees
by: Fatahyah, Yahya
Published: (2016)

A combined theoretical and experimental study of the structure and vibrational adsorption, vibrational circular dichroism, Raman and Raman optical activity spectra of the L-histidine zwitterion
by: Deplazes, Evelyne, et al.
Published: (2007)

Critical Success Factors Influencing Adoption of Internet Technology by MSC & Non-MSC Companies
by: Yew King, lloyd Tam
Published: (2002)

Characterisation of the structure and oligomerisation of islet amyloid polypeptides (IAPP): A review of molecular dynamics simulation studies
by: Moore, S., et al.
Published: (2018)

MSc Entrepreneurship Business Plan
by: Parekh, Priyal
Published: (2009)

Congratulations MScTILS Graduates
by: Noor Raha, Mohd Radzuan
Published: (2022)

Inisiatif terbaru MSC Malaysia
Published: (2008)

MSc Counselling Promotion Slides
by: Fatahyah, Yahya
Published: (2016)

MSC: don't forget Sarawak
by: The People's Mirror
Published: (1996)

MSc Learning Sciences Brochure
by: Universiti Malaysia Sarawak, Centre for Graduate Studies
Published: (2016)

Simulation and Analysis of Short Channel Effects on Bulk and Tri-Gate Multiple Input Floating Gate Mosfet
by: Mohd Maarof, Siti Nuur Basmin
Published: (2008)

Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNaV1.7
by: Agwa, A., et al.
Published: (2017)

Experimental study on the effect of coarse aggregate type on mechanical properties of high strenght concrete
by: Cathy Aqunia, Anak Roderick Sube.
Published: (2004)

Engineering properties of concrete coarsely crushed cockle shell as coarse aggregate replacement
by: Teh, Gek Yu
Published: (2013)

Polypeptide and Protein Modeling for Drug Design
by: O'Mara, M., et al.
Published: (2014)

Experimental study of wood chip as partial replacement for coarse aggregate with ratio 5%, 10 and 15%
by: Mohamad Hafiz, Mohd Salehim
Published: (2017)

CRM Strategies In MSC Status Companies
by: Zafar, Mohammad Afnan
Published: (2007)

MSc Business Plan (Brand X)
by: Thapa, Prajol
Published: (2016)

Looking through the Corridor: Malaysia and the MSC
by: Leong, Susan
Published: (2008)