Structural Investigation of MscL Gating Using Experimental Data and Coarse Grained MD Simulations

The mechanosensitive channel of large conductance (MscL) has become a model system in which to understand mechanosensation, a process involved in osmoregulation and many other physiological functions. While a high resolution closed state structure is available, details of the open structure and the...

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Bibliographic Details
Main Authors: Deplazes, Evelyne, Louhivuori, M., Jayatilaka, D., Marrink, S., Corry, B.
Format: Journal Article
Published: 2012
Online Access:http://hdl.handle.net/20.500.11937/4858