Dietary Iron Enhances Colonic Inflammation and IL-6/IL-11-Stat3 Signaling Promoting Colonic Tumor Development in Mice
Chronic intestinal inflammation and high dietary iron are associated with colorectal cancer development. The role of Stat3 activation in iron-induced colonic inflammation and tumorigenesis was investigated in a mouse model of inflammation-associated colorectal cancer. Mice, fed either an iron-supple...
| Main Authors: | , , , , , , , , |
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| Format: | Journal Article |
| Published: |
Public Library of Science
2013
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| Online Access: | http://hdl.handle.net/20.500.11937/48254 |