Could a loss of memory T cells limit responses to hepatitis C virus (HCV) antigens in blood leucocytes from patients chronically infected with HCV before and during pegylated interferon-a and ribavirin therapy?

Could a loss of memory T cells limit responses to hepatitis C virus (HCV) antigens in blood leucocytes from patients chronically infected with HCV before and during pegylated interferon-a and ribavirin therapy?

The proportions and activation status of T cells may influence responses to hepatitis C virus (HCV) and treatment outcome in patients receiving pegylated interferon (IFN)-a/ribavirin therapy. We confirmed that IFN-? enzyme-linked immunospot (ELISPOT) responses to HCV are poor in HCV patients and sho...

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Bibliographic Details
Main Authors: Lee, S., Hammond, T., Watson, M., Flexman, J., Cheng, W., Fernandez, S., Price, Patricia
Format: Journal Article
Published: 2010
Online Access:http://hdl.handle.net/20.500.11937/4814

Internet

http://hdl.handle.net/20.500.11937/4814

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