The Scar-in-a-Jar: studying potential anti?brotic compounds from the epigenetic to extracellular level in a single well

Background and purpose: Fibrosis, a pathological accumulation of collagen in tissues, represents a major global disease burden. Effective characterization of potential antifibrotic drugs has been constrained by poor formation of the extracellular matrix in vitro, due to tardy procollagen processing...

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Bibliographic Details
Main Authors: Chen, C., Peng, Y., Wang, Z., Fish, P., Kaar, J., Koepsel, R., Russell, A., Lareu, Ricardo, Raghunath, M.
Format: Journal Article
Published: Stockton Press 2009
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/47489