Secondary amine catalyzed retro-aldol reactions of enals and enones: one-pot conversion of enals to [alpha]-substituted derivatives
A practical synthetic procedure to hydrolytically cleave the C,C-double bond of a,b-unsaturated aldehydes and ketones has been developed. Secondary amines are employed as organocatalysts for the retro-aldol process under simple and mild reaction conditions. Beside the generation of the parent aromat...
| Main Authors: | , |
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| Format: | Journal Article |
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Pergamon
2012
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0040403912002663 http://hdl.handle.net/20.500.11937/4742 |