Comparative analysis of the surface interaction properties of the binding sites of CDK2, CDK4 and ERK2
Recently developed hydrogen-bonding and hydrophobic analysis algorithms were used to investigate the interaction properties of the ATP binding sites of CDK2, CDK4, and ERK2. We were able to prioritise those hydrogen-bonding groups that are observed to bind the native ATP ligand, as well as to identi...
| Main Authors: | , |
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| Format: | Journal Article |
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Wiley-VCH Verlag GmbH & Co. KGaA
2006
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| Online Access: | http://hdl.handle.net/20.500.11937/47295 |