Barnacle: Detecting and characterizing tandem duplications and fusions in transcriptome assemblies

Barnacle: Detecting and characterizing tandem duplications and fusions in transcriptome assemblies

Background: Chimeric transcripts, including partial and internal tandem duplications (PTDs, ITDs) and gene fusions, are important in the detection, prognosis, and treatment of human cancers.Results: We describe Barnacle, a production-grade analysis tool that detects such chimeras in de novo assembli...

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Bibliographic Details
Main Authors: Swanson, L., Robertson, G., Mungall, K., Butterfield, Y., Chiu, R., Corbett, R., Docking, T., Hogge, D., Jackman, S., Moore, R., Mungall, A., Nip, K., Parker, J., Qian, J., Raymond, A., Sung, S., Tam, A., Thiessen, N., Varhol, Richard, Wang, S., Yorukoglu, D., Zhao, Y., Hoodless, P., Sahinalp, S., Karsan, A., Birol, I.
Format: Journal Article
Published: 2013
Online Access:http://hdl.handle.net/20.500.11937/46752

Internet

http://hdl.handle.net/20.500.11937/46752

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