Optimization of PLGA nanoparticles formulation containing L-DOPA by applying the central composite design

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Optimization of PLGA nanoparticles formulation containing L-DOPA by applying the central composite design

The aim of this work was to prepare L-DOPA loaded poly(d,l-lactide-co-glycolide) (PLGA) nanoparticles by a modified water-in-oil-in-water (W1/O/W2) emulsification solvent evaporation method. A central composite design was applied for optimization of the formulation parameters and for studying the ef...

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Bibliographic Details
Main Authors:	Zhou, Yong Zhi, Alany, Raid, Chuang, Victor, Wen, Jingyuan
Format:	Journal Article
Published:	Informa Healthcare 2013
Online Access:	http://hdl.handle.net/20.500.11937/45363

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