Optimization of PLGA nanoparticles formulation containing L-DOPA by applying the central composite design
The aim of this work was to prepare L-DOPA loaded poly(d,l-lactide-co-glycolide) (PLGA) nanoparticles by a modified water-in-oil-in-water (W1/O/W2) emulsification solvent evaporation method. A central composite design was applied for optimization of the formulation parameters and for studying the ef...
| Main Authors: | , , , |
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| Format: | Journal Article |
| Published: |
Informa Healthcare
2013
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| Online Access: | http://hdl.handle.net/20.500.11937/45363 |