Platelet-VWF complexes get the chop

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Platelet-VWF complexes get the chop

In this issue of Blood, Shim and colleagues define a dual role for platelet glycoprotein (GP)Iba (the major ligand-binding subunit of the GPIb-IX-V complex) in regulating ADAMTS13-mediated cleavage of von Willebrand factor (VWF) under shear: it alleviates an inhibitory effect of the VWFA1 domain on...

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Bibliographic Details
Main Authors:	Berndt, Michael, Andrews, R.
Format:	Journal Article
Published:	American Society of Hematology 2008
Online Access:	http://hdl.handle.net/20.500.11937/45221

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