Platelet-VWF complexes get the chop
In this issue of Blood, Shim and colleagues define a dual role for platelet glycoprotein (GP)Iba (the major ligand-binding subunit of the GPIb-IX-V complex) in regulating ADAMTS13-mediated cleavage of von Willebrand factor (VWF) under shear: it alleviates an inhibitory effect of the VWFA1 domain on...
| Main Authors: | , |
|---|---|
| Format: | Journal Article |
| Published: |
American Society of Hematology
2008
|
| Online Access: | http://hdl.handle.net/20.500.11937/45221 |