Receptor activator of NF-κB ligand promotes proliferation of a putative mammary stem cell unique to the lactating epithelium

Receptor activator of NF-κB ligand promotes proliferation of a putative mammary stem cell unique to the lactating epithelium

In mice, CD49fhi mammary stem cells (MaSCs) asymmetrically divide to generate CD49f+ committed progenitor cells that differentiate into CD49f− phenotypes of the milk-secreting tissue at the onset of pregnancy. We show CD49f+ primary mammary epithelial cells (PMECs) isolated from lactating tissue uni...

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Bibliographic Details
Main Authors: Thomas, E., Lee-Pullen, T., Rigby, P., Hartmann, P., Xu, J., Zeps, Nikolajs
Format: Journal Article
Published: 2012
Online Access:http://hdl.handle.net/20.500.11937/45110

Internet

http://hdl.handle.net/20.500.11937/45110

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