Chiral analysis of methadone and its major metabolites (EDDP and EMDP) by liquid chromatography–mass spectrometry
Racemic methadone (MET) is administered to heroin users undergoing methadone maintenance therapy (MMT) in Australia. The enantiomers of methadone possess different pharmacological effects, and the enantioselective metabolism of methadone to its two major metabolites, 2-ethylidene-1,5-dimethyl-3,3-di...
| Main Authors: | , , |
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| Format: | Journal Article |
| Published: |
Elsevier
2005
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| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.11937/44826 |
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