Synthesis and Antileukemic Activity of New Fluorinated 5-Aza-9-deazapurines

Novel fluorinated 4-benzylamino-7-phenylpyrazolo[1,5-a]- [1,3,5]triazin-2-amines were prepared using an efficient and practical approach. The chemoselectivity of condensation of pyrazolylguanidine and trichloroacetonitrile was found to be solvent-dependent and, when conducted in toluene, this reacti...

Full description

Bibliographic Details
Main Authors: Lim, F., Kow, K., Yeo, E., Chow, S., Dolzhenko, Anton
Format: Journal Article
Published: The Japan Institute of Heterocyclic Chemistry 2016
Online Access:http://hdl.handle.net/20.500.11937/44647