A possible role for metallic ions in the carbohydrate cluster recognition displayed by a lewis Y specific antibody
Background: Lewis Y (Ley) is a blood group-related carbohydrate that is expressed at high surface densities on the majority of epithelial carcinomas and is a promising target for antibody-based immunotherapy. A humanized Ley-specific antibody (hu3S193) has shown encouraging safety, pharmacokinetic a...
| Main Authors: | , , |
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| Format: | Journal Article |
| Published: |
Public Library of Science
2009
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| Online Access: | http://hdl.handle.net/20.500.11937/44468 |