Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-κB regulated gene products in multiple myeloma xenograft mouse model

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Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-κB regulated gene products in multiple myeloma xenograft mouse model

Multiple myeloma (MM) is a B cell malignancy characterized by clonal proliferation of plasma cells in the bone marrow. With the advent of novel targeted agents, the median survival rate has increased to 5 -7 years. However, majority of patients with myeloma suffer relapse or develop chemoresistance...

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Bibliographic Details
Main Authors:	Siveen, K., Mustafa, N., Li, F., Kannaiyan, R., Ahn, K., Kumar, Alan Prem, Chng, W., Sethi, G.
Format:	Journal Article
Published:	Impact Journals LLC 2014
Online Access:	http://hdl.handle.net/20.500.11937/44202

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