Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-κB regulated gene products in multiple myeloma xenograft mouse model
Multiple myeloma (MM) is a B cell malignancy characterized by clonal proliferation of plasma cells in the bone marrow. With the advent of novel targeted agents, the median survival rate has increased to 5 -7 years. However, majority of patients with myeloma suffer relapse or develop chemoresistance...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Journal Article |
| Published: |
Impact Journals LLC
2014
|
| Online Access: | http://hdl.handle.net/20.500.11937/44202 |