Serum marker of inflammasome activity correlates with liver injury in nonalcoholic fatty liver disease and is influenced by genetic polymorphisms

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Serum marker of inflammasome activity correlates with liver injury in nonalcoholic fatty liver disease and is influenced by genetic polymorphisms

Background and Aims: The NLRP3 inflammasome has been implicated in the pathogenesis of liver injury in nonalcoholic fatty liver disease (NAFLD). In humans, mutations of Nlrp3 have functional consequences and result in auto-inflammatory syndromes. We examined whether single nucleotide polymorphisms (...

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Bibliographic Details
Main Authors:	Adams, L., Wree, A., Melton, P., Jeffrey, G., Ching, H., de Boer, B., Olynyk, J., Ayonrinde, O., Mori, T., Beilin, L., Price, Patricia, Pennell, C., Eslam, M., George, J., Feldstein, A.
Format:	Conference Paper
Published:	2015
Online Access:	http://hdl.handle.net/20.500.11937/44199

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