Serum marker of inflammasome activity correlates with liver injury in nonalcoholic fatty liver disease and is influenced by genetic polymorphisms

Serum marker of inflammasome activity correlates with liver injury in nonalcoholic fatty liver disease and is influenced by genetic polymorphisms

Background and Aims: The NLRP3 inflammasome has been implicated in the pathogenesis of liver injury in nonalcoholic fatty liver disease (NAFLD). In humans, mutations of Nlrp3 have functional consequences and result in auto-inflammatory syndromes. We examined whether single nucleotide polymorphisms (...

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Bibliographic Details
Main Authors: Adams, L., Wree, A., Melton, P., Jeffrey, G., Ching, H., de Boer, B., Olynyk, J., Ayonrinde, O., Mori, T., Beilin, L., Price, Patricia, Pennell, C., Eslam, M., George, J., Feldstein, A.
Format: Conference Paper
Published: 2015
Online Access:http://hdl.handle.net/20.500.11937/44199

Internet

http://hdl.handle.net/20.500.11937/44199

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