Effects of a high-fat, high-cholesterol diet on brain lipid profiles in apolipoprotein E ε3 and ε4 knock-in mice

Effects of a high-fat, high-cholesterol diet on brain lipid profiles in apolipoprotein E ε3 and ε4 knock-in mice

Apolipoprotein E (ApoE) is important in facilitating the transport of lipids (cholesterol, phospholipids, and sulfatides) and plays a fundamental role in normal lipid metabolism. High cholesterol levels increases the risk of developing Alzheimer’s disease. In this study, we investigated the effects...

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Bibliographic Details
Main Authors: Lim, Wei Ling, Lam, Sin Man, Shui, Guanghou, Mondal, Alinda, Ong, Daniel, Duan, Xinrui, Creegan, Rhona, martins, Ian, Sharman, Matthew, Taddei, Kevin, Verdile, Giuseppe, Wenk, Markus, Martins, Ralph
Format: Journal Article
Published: Elsevier Inc. 2013
Subjects:
High cholesterol
Mass spectrometry
High fat
Oxysterols
APOE KI mice
Glycerophospholipids
Online Access:http://hdl.handle.net/20.500.11937/44156

Internet

http://hdl.handle.net/20.500.11937/44156

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