Human serum albumin-thioredoxin fusion protein with long blood retention property is effective in suppressing lung injury

Thioredoxin (Trx) is a redox-active protein with anti-inflammatory effects but with a short half life of 1 h. Genetic fusion of Trx to human serum albumin (HSA) extended its half life without causing significant loss of its biological activities. HSA–Trx caused a decrease in the number of cells in b...

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Bibliographic Details
Main Authors: Furukawa, M., Tanaka, R., Chuang, Victor, Ishima, Y., Taguchi, K., Watanabe, H., Maruyama, T., Otagiri, M.
Format: Journal Article
Published: Elsevier 2011
Online Access:http://hdl.handle.net/20.500.11937/43717