Rapid detection of H and R Panton-Valentine leukocidin isoforms in Staphylococcus aureus by high-resolution melting analysis

We designed a single-step, closed-tube, real-time polymerase chain reaction and high-resolution melting assay to simultaneously detect the presence of the Panton-Valentine leukocidin gene and discriminate histidine and arginine isoforms. Of 223 Staphylococcus aureus isolates from northern Australia,...

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Main Authors: Tong, S., Lilliebridge, R., Holt, D., Coombs, Geoffrey, Currie, B., Giffard, P.
Format: Journal Article
Published: Elsevier 2010
Online Access:http://hdl.handle.net/20.500.11937/43704
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author Tong, S.
Lilliebridge, R.
Holt, D.
Coombs, Geoffrey
Currie, B.
Giffard, P.
author_facet Tong, S.
Lilliebridge, R.
Holt, D.
Coombs, Geoffrey
Currie, B.
Giffard, P.
author_sort Tong, S.
building Curtin Institutional Repository
collection Online Access
description We designed a single-step, closed-tube, real-time polymerase chain reaction and high-resolution melting assay to simultaneously detect the presence of the Panton-Valentine leukocidin gene and discriminate histidine and arginine isoforms. Of 223 Staphylococcus aureus isolates from northern Australia, isoforms clustered by clonal complex (CC). All CC93 isolates harbored the arginine isoform. © 2010.
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format Journal Article
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institution Curtin University Malaysia
institution_category Local University
last_indexed 2025-11-14T09:17:38Z
publishDate 2010
publisher Elsevier
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spelling curtin-20.500.11937-437042017-09-13T13:37:33Z Rapid detection of H and R Panton-Valentine leukocidin isoforms in Staphylococcus aureus by high-resolution melting analysis Tong, S. Lilliebridge, R. Holt, D. Coombs, Geoffrey Currie, B. Giffard, P. We designed a single-step, closed-tube, real-time polymerase chain reaction and high-resolution melting assay to simultaneously detect the presence of the Panton-Valentine leukocidin gene and discriminate histidine and arginine isoforms. Of 223 Staphylococcus aureus isolates from northern Australia, isoforms clustered by clonal complex (CC). All CC93 isolates harbored the arginine isoform. © 2010. 2010 Journal Article http://hdl.handle.net/20.500.11937/43704 10.1016/j.diagmicrobio.2010.03.015 Elsevier restricted
spellingShingle Tong, S.
Lilliebridge, R.
Holt, D.
Coombs, Geoffrey
Currie, B.
Giffard, P.
Rapid detection of H and R Panton-Valentine leukocidin isoforms in Staphylococcus aureus by high-resolution melting analysis
title Rapid detection of H and R Panton-Valentine leukocidin isoforms in Staphylococcus aureus by high-resolution melting analysis
title_full Rapid detection of H and R Panton-Valentine leukocidin isoforms in Staphylococcus aureus by high-resolution melting analysis
title_fullStr Rapid detection of H and R Panton-Valentine leukocidin isoforms in Staphylococcus aureus by high-resolution melting analysis
title_full_unstemmed Rapid detection of H and R Panton-Valentine leukocidin isoforms in Staphylococcus aureus by high-resolution melting analysis
title_short Rapid detection of H and R Panton-Valentine leukocidin isoforms in Staphylococcus aureus by high-resolution melting analysis
title_sort rapid detection of h and r panton-valentine leukocidin isoforms in staphylococcus aureus by high-resolution melting analysis
url http://hdl.handle.net/20.500.11937/43704