Effect of the incorporation of hydroxy-terminated liquid silicones on the cure characteristics, morphology and release of a model protein from silicone elastomer covered rods

Silicone elastomer systems have previously been shown to offer potential for the sustained release of protein therapeutics. However, the general requirement for the incorporation of large amounts of release enhancing solid excipients to achieve therapeutically effective release rates from these othe...

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Bibliographic Details
Main Authors: McConville, Christopher, Andrews, G., Woolfson, A., Malcolm, R.
Format: Journal Article
Published: John Wiley and Sons Inc 2011
Online Access:http://hdl.handle.net/20.500.11937/43153