Direct radical scavenging activity of benzbromarone provides beneficial antioxidant properties for hyperuricemia treatment

Uric acid exerts an important antioxidant effect against external oxidative stress under physiological conditions. However, uric acid itself can increase oxidative stress via reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase activation in adipocytes and vascular cells. Uric acid tr...

Full description

Bibliographic Details
Main Authors: Kadowaki, D., Sakaguchi, S., Miyamoto, Y., Taguchi, K., Muraya, N., Narita, Y., Sato, K., Chuang, Victor, Maruyama, T., Otagiri, M., Hirata, S.
Format: Journal Article
Published: Pharmaceutical Society of Japan 2015
Online Access:http://hdl.handle.net/20.500.11937/42816