Molecular dynamics simulations of mixed DOPC-ß-sitosterol bilayers and their interactions with DMSO

ell membrane phospholipid bilayers can be damaged by the large amounts of dimethyl sulphoxide (DMSO) commonly used in cryopreservation. The interaction of DMSO with model bilayers consisting of 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) and ß-sitosterol has been studied using molecular dynamics...

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Bibliographic Details
Main Authors: Hughes, Zak, Mancera, Ricardo
Format: Journal Article
Published: RSC Publishing 2013
Online Access:http://hdl.handle.net/20.500.11937/42712