Alzheimer's amyloid-ß rescues yeast from hydroxide toxicity

Amyloid-ß (Aß-{42}), which is known to be toxic to neuronal cells, protects yeast cells from severe sodium hydroxide toxicity. More than 85% cell death was caused by treatment with 1 mM NaOH and approximately 95% was observed at a 2 mM concentration. However, greater than 55% cells survived the trea...

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Bibliographic Details
Main Authors: Dubey, A., Bharadwaj, Prashant, Varghese, J., MacReadie, I.
Format: Journal Article
Published: IOS Press 2009
Online Access:http://hdl.handle.net/20.500.11937/42488