The intrahepatic signalling niche of hedgehog is defined by primary cilia positive cells during chronic liver injury

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The intrahepatic signalling niche of hedgehog is defined by primary cilia positive cells during chronic liver injury

Background & Aims: In vertebrates, canonical Hedgehog (Hh) pathway activation requires Smoothened (SMO) translocation to the primary cilium (Pc), followed by a GLI-mediated transcriptional response. In addition, a similar gene regulation occurs in response to growth factors/cytokines, although i...

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Bibliographic Details
Main Authors:	Grzelak, C., Martelotto, L., Sigglekow, N., Patkunanathan, B., Ajami, K., Calabro, S., Dwyer, Benjamin, Tirnitz-Parker, Janina, Watkins, D., Warner, F., Shackel, N., McCaughan, G.
Format:	Journal Article
Published:	Elsevier BV 2014
Online Access:	http://hdl.handle.net/20.500.11937/42482

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