The intrahepatic signalling niche of hedgehog is defined by primary cilia positive cells during chronic liver injury
Background & Aims: In vertebrates, canonical Hedgehog (Hh) pathway activation requires Smoothened (SMO) translocation to the primary cilium (Pc), followed by a GLI-mediated transcriptional response. In addition, a similar gene regulation occurs in response to growth factors/cytokines, although i...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Journal Article |
| Published: |
Elsevier BV
2014
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| Online Access: | http://hdl.handle.net/20.500.11937/42482 |