Pharmacokinetics, Pharmacodynamics and Allometric Scaling of Chloroquine in a Murine Malaria Model

Chloroquine (CQ) is an important antimalarial drug for the treatment of special patient groups and as a comparator for preclinical testing of new drugs. Pharmacokinetic data for CQ in animal models are limited; thus, we conducted a three-part investigation, comprising (i) pharmacodynamic studies of...

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Bibliographic Details
Main Authors: Moore, Brioni, Page-Sharp, Madhu, Stoney, Jillian, Ilett, K., Jago, Jeffrey, Batty, Kevin
Format: Journal Article
Published: American Society for Microbiology 2011
Online Access:http://hdl.handle.net/20.500.11937/42367