The impact of cryopreservation on human peripheral blood leucocyte bioenergetics

This study has demonstrated for the first time that cryopreservation of primary immune cells modified their metabolism in a time-dependent fashion, indicated by attenuated aerobic respiration and enhanced glycolytic activity. Measurements were recorded using the Seahorse XFe96 extracellular flux ana...

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Bibliographic Details
Main Authors: Keane, Kevin, Calton, E., Cruzat, Vinicius, Soares, M., Newsholme, Philip
Format: Journal Article
Published: 2015
Online Access:http://hdl.handle.net/20.500.11937/42333