A uremic toxin 3-carboxy-4-methyl-5-propyl-2-furanpropionate accumulates in proximal tubular cells and induces cell damage through increasing oxidative stress

Introduction and Aims: 3-Carboxy-4-methyl-5-propyl-2-furanpropionate (CMPF) is a furan fatty acid derivative, a uremic toxin and a substrate of transporters for organic anions that contribute to the accumulation of CMPF in renal tubular cells. However, information regarding cytotoxicity of CMPF is l...

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Bibliographic Details
Main Authors: Miyamoto, Y., Iwao, Y., Watanabe, H., Kadowaki, D., Ishima, Y., Chuang, Victor, Sato, K., Otagiri, M., Maruyama, T.
Other Authors: Carmine Zoccali
Format: Conference Paper
Published: Oxford University Press 2012
Online Access:http://hdl.handle.net/20.500.11937/42244