Immunosenescent CD57 +CD4+ T-cells accumulate and contribute to interferon-γ responses in HIV patients responding stably to ART

QR Code

Immunosenescent CD57 +CD4+ T-cells accumulate and contribute to interferon-γ responses in HIV patients responding stably to ART

HIV-infected individuals responding to antiretroviral therapy (ART) after severe CD4+ T-cell depletion may retain low responses to recall antigens [eg: cytomegalovirus (CMV)] and altered expression of T-cell co-stimulatory molecules consistent with immunosenescence. We investigated the capacity of p...

Full description

Bibliographic Details
Main Authors:	Fernandez, S., French, M., Price, Patricia
Format:	Journal Article
Published:	2011
Online Access:	http://hdl.handle.net/20.500.11937/4217

Similar Items

CD31 (PECAM-1) is a marker of recent thymic emigrants among CD4+ T-cells, but not CD8+ T-cells or ? d T-cells, in HIV patients responding to ART
by: Tanaskovic, S., et al.
Published: (2010)

CD4 + T-cell deficiency in HIV patients responding to antiretroviral therapy is associated with increased expression of interferon-stimulated genes in CD4 + T cells
by: Fernandez, S., et al.
Published: (2011)

Impaired Upregulation of the Costimulatory Molecules, CD27 and CD28, on CD4(+) T Cells from HIV Patients Receiving ART Is Associated with Poor Proliferative Responses.
by: Tanaskovic, S., et al.
Published: (2016)

Naive and Memory CD4+ T Cells Are Differentially Affected in Indonesian HIV Patients Responding to ART
by: Tanaskovic, S., et al.
Published: (2016)

Could natural killer cells compensate for impaired CD4+ T-cell responses to CMV in HIV patients responding to antiretroviral therapy?
by: Tan, D., et al.
Published: (2009)

Robust interferon-a and IL-12 responses by dendritic cells are related to efficient CD4+ T-cell recovery in HIV patients on ART
by: Tan, D., et al.
Published: (2011)

The number and function of circulating dendritic cells may limit effector memory CD4+ T-cell responses in HIV patients responding to antiretroviral therapy
by: Fernandez, S., et al.
Published: (2008)

Nadir CD4 T-cell counts continue to influence interferon-? responses in HIV patients who began antiretroviral treatment with advanced immunodeficiency
by: Price, Patricia, et al.
Published: (2008)

Interleukin-7 signalling defects in naive CD4+ T cells of HIV patients with CD4+ T-cell deficiency onantiretroviral therapy are associated with T-cell activation and senescence
by: Tanaskovic, S., et al.
Published: (2014)

CD4+ and CD8+ T cells expressing FoxP3 in HIV-infected patients are phenotypically distinct and influenced by disease severity and antiretroviral therapy
by: Lim, A., et al.
Published: (2009)

Periportal CD4+ Cell Infiltration Increases in HIV/Hepatitis C Virus–Coinfected Patients Commencing ART, Whereas CD8+ Cells Clear From the Liver
by: Gani, R., et al.
Published: (2014)

Thymic tissue is not evident on high-resolution computed tomography and [18F]Fluoro-deoxy-glucose positron emission tomography scans of aviraemic HIV patients with poor recovery of CD4 + T cells
by: Tanaskovic, S., et al.
Published: (2011)

Chemokine receptor expression on dendritic cells is normal in HIV-infected patients with a stable response to ART, but chemokine levels remain elevated
by: Lee, S., et al.
Published: (2011)

Toll-like receptor (TLR) expression on CD4+ and CD8+ T-cells in patients chronically infected with hepatitis C virus
by: Hammond, T., et al.
Published: (2010)

Increased proportion of the CD56bright NK cell subset in patients chronically infected with Hepatitis C Virus (HCV) receiving interferon-a and ribavirin therapy
by: Lee, S., et al.
Published: (2010)

Interferon-? and IL-5 production correlate directly in HIV patients Co-infected with mycobacterium tuberculosis with or without immune restoration disease
by: Oliver, B., et al.
Published: (2010)

Increased proportions of dendritic cells and recovery of IFNγ responses in HIV/HCV co-infected patients receiving ART
by: Saraswati, H., et al.
Published: (2015)

CD95 recruits PLCγ1 to trigger a calcium response promoting Th17 accumulation in inflamed organs of lupus mice
by: Poissonnier, Amanda, et al.
Published: (2016)

Expression of interleukin-18, interferon-γ and interleukin-10 in hepatocellular carcinoma
by: Chia, Chok Seng, et al.
Published: (2002)

Polymorphisms in IL10 may alter CD4 T-cell counts in Indonesian HIV patients beginning antiretroviral therapy
by: Dmello, D., et al.
Published: (2017)

Lipid-laden partially-activated plasmacytoid and CD4-CD8a+ dendritic cells accumulate in tissues in elderly mice
by: Gardner, Joanne, et al.
Published: (2014)

Prevalence of classical CD14++/CD16 - But not of intermediate CD14++/CD16 + monocytes in hypoalphalipoproteinemia
by: Sala, F., et al.
Published: (2013)

Accumulation Characteristics Of Centella Asiatica L. As A Potential Cd-hyperaccumulator In Soil
by: Sarji, Noor Liyana
Published: (2016)

Accumulation Characteristics Of Centella Asiatica L. As A Potential Cd-hyperaccumulator In Soil
by: Sarji, Noor Liyana
Published: (2016)

CD56+ lymphocyte counts remain low in the livers of human immunodeficiency virus/hepatitis C virus patients commencing ART
by: Susufi, Y., et al.
Published: (2015)

Juxtaposition of system dynamics and agent-based simulation for a case study in immunosenescence
by: Figueredo, Grazziela P., et al.
Published: (2015)

Electrodeposited CdS/CdTe solar cells
by: Mohamad, Souad A.
Published: (2011)

IL-36α induces maturation of Th1-inducing human MDDC and synergises with IFN-γ to induce high surface expression of CD14 and CD11c
by: Higgins, John, et al.
Published: (2015)

CD4-binding site alterations in CCR5-using HIV-1 envelopes influencing gp120-CD4 interactions and fusogenicity
by: Sterjovski, J., et al.
Published: (2011)

Characteristics of natural killer cells in Malaysian HIV patients presenting with immune restoration disease after ART
by: Tan, D., et al.
Published: (2010)

Immune restoration disease complicating antiretroviral therapy in patients with HIV infection: Implications and solutions
by: French, M., et al.
Published: (2008)

An evaluation of CD39 as a novel immunoregulatory mechanism invoked by COPD
by: Tan, D., et al.
Published: (2016)

Conformational alterations in the CD4 binding cavity of HIV-1 gp120 influencing gp120-CD4 interactions and fusogenicity of HIV-1 envelopes derived from brain and other tissues
by: Gray, L., et al.
Published: (2011)

Interferon-gamma (IFN-γ): reviewing its mechanisms and signaling pathways on the regulation of endothelial barrier function
by: Ng, Chin Theng, et al.
Published: (2023)

Elderly dendritic cells respond to LPS/IFN-Î³ and CD40L stimulation despite incomplete maturation
by: Gardner, J., et al.
Published: (2018)

CD4/CD8 Ratios among Blood Donors in Penang
by: Musa, M, et al.
Published: (1990)

Singly diagonally implicit block backward differentiation formulas for HIV infection of CD4+T cells
by: Jana Aksah, Saufianim, et al.
Published: (2019)

The immunological footprint of CMV in HIV-1 patients stable on long-term ART
by: Affandi, J., et al.
Published: (2015)

HIV patients stable on ART retain evidence of a high CMV load but changes to Natural Killer cell phenotypes reflect both HIV and CMV
by: Affandi, J., et al.
Published: (2015)

A short review of CdTe and CdSe films: growth and characterization
by: Ho, Soon Min, et al.
Published: (2018)

Cannot write session to /tmp/vufind_sessions/sess_c9fduru9e6b3ddfdtrne2fa2pn