Immunosenescent CD57 +CD4+ T-cells accumulate and contribute to interferon-γ responses in HIV patients responding stably to ART

HIV-infected individuals responding to antiretroviral therapy (ART) after severe CD4+ T-cell depletion may retain low responses to recall antigens [eg: cytomegalovirus (CMV)] and altered expression of T-cell co-stimulatory molecules consistent with immunosenescence. We investigated the capacity of p...

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Bibliographic Details
Main Authors: Fernandez, S., French, M., Price, Patricia
Format: Journal Article
Published: 2011
Online Access:http://hdl.handle.net/20.500.11937/4217