Computational Studies of Novel Chymase Inhibitors Against Cardiovascular and Allergic Diseases: Mechanism and Inhibition

To provide a new idea for drug design, a computational investigation is performed on chymase and its novel 1,4-diazepane-2,5-diones inhibitors that explores the crucial molecular features contributing to binding specificity. Molecular docking studies of inhibitors within the active site of chymase w...

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Bibliographic Details
Main Authors: Arooj, Mahreen, Thangapandian, S., John, S., Hwang, S., Park, J., Lee, K.
Format: Journal Article
Published: 2012
Online Access:http://hdl.handle.net/20.500.11937/41921