Cyclic Dipeptide Shuttles as a Novel Skin Penetration Enhancement Approach: Preliminary Evaluation with Diclofenac
This study demonstrates the effectiveness of a peptide shuttle in delivering diclofenac into and through human epidermis. Diclofenac was conjugated to a novel phenylalanyl-N-methyl-naphthalenylalanine-derived diketopiperazine (DKP) shuttle and to TAT (a classical cell penetrating peptide), and topic...
| Main Authors: | , , , , |
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| Format: | Journal Article |
| Published: |
Public Library of Science
2016
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| Online Access: | http://hdl.handle.net/20.500.11937/4171 |