Effects of lupin-enriched foods on body composition and cardiovascular disease risk factors: a 12-month randomized controlled weight loss trial
Background: Regular consumption of diets with increased protein or fibre intakes may benefit body weight and composition and cardiovascular disease risk factors. Lupin flour is a novel food ingredient high in protein and fibre.Objective: To investigate the effects of a lupin-enriched diet, during an...
| Main Authors: | , , , , , , , , , , |
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| Format: | Journal Article |
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Nature Publishing Group
2011
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| Online Access: | http://hdl.handle.net/20.500.11937/41393 |
| _version_ | 1848756133581291520 |
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| author | Belski, R. Mori, T. Puddey, I. Sipsas, S. Woodman, R. Ackland, T. Dove, E. Carlyon, N. Jayasena, Vijay Hodgson, J. Beilin, L. |
| author_facet | Belski, R. Mori, T. Puddey, I. Sipsas, S. Woodman, R. Ackland, T. Dove, E. Carlyon, N. Jayasena, Vijay Hodgson, J. Beilin, L. |
| author_sort | Belski, R. |
| building | Curtin Institutional Repository |
| collection | Online Access |
| description | Background: Regular consumption of diets with increased protein or fibre intakes may benefit body weight and composition and cardiovascular disease risk factors. Lupin flour is a novel food ingredient high in protein and fibre.Objective: To investigate the effects of a lupin-enriched diet, during and following energy restriction, on body weight and composition and cardiovascular disease risk factors in overweight individuals.Design: Participants (n=131) were recruited to a 12-month parallel-design trial. They were randomly assigned to consume lupin-enriched foods or matching high-carbohydrate control foods. All participants underwent 3 months of weight loss, 1 month of weight stabilization and 8 months of weight maintenance. Body weight and composition and cardiovascular disease risk factors were assessed at baseline, 4 and 12 months.Results: Lupin, relative to control, did not significantly influence (mean difference (95% CI)) weight loss at 4 months (0.1?kg (-1.2, 1.4)) and 12 months (-0.6?kg (-2.0, 0.8)), maintenance of weight loss from 4 to 12 months (-0.7?kg (-1.83, 0.48)) or measures of body fat and fat-free mass. Relative to control, 24-h ambulatory systolic (-1.3?mm?Hg (-2.4, -0.3), P=0.016) and diastolic (-1.0?mm?Hg (-1.9, -0.2), P=0.021) blood pressures were lower at 12 months but not at 4 months; fasting insulin concentrations and homeostasis model assessment (HOMA) scores were significantly lower at 4 months (-1.2?mU?l–1 (-1.3, -1.1), P=0.004 and -0.6 units (-1.0, -0.19), P=0.004) and 12 months (-1.3 mU?l–1 (-1.4, -1.1), P<0.001 and -0.7 units (-1.1, -0.24), P=0.002).Conclusions: A diet higher in protein and fibre derived from lupin-enriched foods does not enhance weight loss or improve the maintenance of weight loss. However, such a diet may provide cardiovascular health benefits in terms of insulin sensitivity and blood pressure. |
| first_indexed | 2025-11-14T09:07:21Z |
| format | Journal Article |
| id | curtin-20.500.11937-41393 |
| institution | Curtin University Malaysia |
| institution_category | Local University |
| last_indexed | 2025-11-14T09:07:21Z |
| publishDate | 2011 |
| publisher | Nature Publishing Group |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | curtin-20.500.11937-413932017-02-28T01:37:51Z Effects of lupin-enriched foods on body composition and cardiovascular disease risk factors: a 12-month randomized controlled weight loss trial Belski, R. Mori, T. Puddey, I. Sipsas, S. Woodman, R. Ackland, T. Dove, E. Carlyon, N. Jayasena, Vijay Hodgson, J. Beilin, L. lipids blood pressure weight loss insulin lupin Background: Regular consumption of diets with increased protein or fibre intakes may benefit body weight and composition and cardiovascular disease risk factors. Lupin flour is a novel food ingredient high in protein and fibre.Objective: To investigate the effects of a lupin-enriched diet, during and following energy restriction, on body weight and composition and cardiovascular disease risk factors in overweight individuals.Design: Participants (n=131) were recruited to a 12-month parallel-design trial. They were randomly assigned to consume lupin-enriched foods or matching high-carbohydrate control foods. All participants underwent 3 months of weight loss, 1 month of weight stabilization and 8 months of weight maintenance. Body weight and composition and cardiovascular disease risk factors were assessed at baseline, 4 and 12 months.Results: Lupin, relative to control, did not significantly influence (mean difference (95% CI)) weight loss at 4 months (0.1?kg (-1.2, 1.4)) and 12 months (-0.6?kg (-2.0, 0.8)), maintenance of weight loss from 4 to 12 months (-0.7?kg (-1.83, 0.48)) or measures of body fat and fat-free mass. Relative to control, 24-h ambulatory systolic (-1.3?mm?Hg (-2.4, -0.3), P=0.016) and diastolic (-1.0?mm?Hg (-1.9, -0.2), P=0.021) blood pressures were lower at 12 months but not at 4 months; fasting insulin concentrations and homeostasis model assessment (HOMA) scores were significantly lower at 4 months (-1.2?mU?l–1 (-1.3, -1.1), P=0.004 and -0.6 units (-1.0, -0.19), P=0.004) and 12 months (-1.3 mU?l–1 (-1.4, -1.1), P<0.001 and -0.7 units (-1.1, -0.24), P=0.002).Conclusions: A diet higher in protein and fibre derived from lupin-enriched foods does not enhance weight loss or improve the maintenance of weight loss. However, such a diet may provide cardiovascular health benefits in terms of insulin sensitivity and blood pressure. 2011 Journal Article http://hdl.handle.net/20.500.11937/41393 Nature Publishing Group restricted |
| spellingShingle | lipids blood pressure weight loss insulin lupin Belski, R. Mori, T. Puddey, I. Sipsas, S. Woodman, R. Ackland, T. Dove, E. Carlyon, N. Jayasena, Vijay Hodgson, J. Beilin, L. Effects of lupin-enriched foods on body composition and cardiovascular disease risk factors: a 12-month randomized controlled weight loss trial |
| title | Effects of lupin-enriched foods on body composition and cardiovascular disease risk factors: a 12-month randomized controlled weight loss trial |
| title_full | Effects of lupin-enriched foods on body composition and cardiovascular disease risk factors: a 12-month randomized controlled weight loss trial |
| title_fullStr | Effects of lupin-enriched foods on body composition and cardiovascular disease risk factors: a 12-month randomized controlled weight loss trial |
| title_full_unstemmed | Effects of lupin-enriched foods on body composition and cardiovascular disease risk factors: a 12-month randomized controlled weight loss trial |
| title_short | Effects of lupin-enriched foods on body composition and cardiovascular disease risk factors: a 12-month randomized controlled weight loss trial |
| title_sort | effects of lupin-enriched foods on body composition and cardiovascular disease risk factors: a 12-month randomized controlled weight loss trial |
| topic | lipids blood pressure weight loss insulin lupin |
| url | http://hdl.handle.net/20.500.11937/41393 |