Efficacy of Continuously Administered PEDF-Derived Synthetic Peptides against Osteosarcoma Growth and Metastasis

The potent antiangiogenic pigment epithelium-derived factor (PEDF) has shown promise against osteosarcoma, a tumour that originates in the bone and metastasises to the lungs. Neurotrophic, antiangiogenic, antiproliferative, and antimetastatic properties of PEDF have been attributed to a number of fu...

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Bibliographic Details
Main Authors: Broadhead, M., Choong, P., Dass, Crispin
Format: Journal Article
Published: Hindawi Publishing Corporation 2012
Online Access:http://hdl.handle.net/20.500.11937/40859