Brain transcriptome perturbations in the Hfe -/- mouse model of genetic iron loading

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Brain transcriptome perturbations in the Hfe -/- mouse model of genetic iron loading

Severe disruption of brain iron homeostasis can cause fatal neurodegenerative disease, however debate surrounds the neurologic effects of milder, more common iron loading disorders such as hereditary hemochromatosis, which is usually caused by loss-of-function polymorphisms in the HFE gene. There is...

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Bibliographic Details
Main Authors:	Johnstone, D., Graham, Ross, Trinder, D., Delima, R., Riveros, C., Olynyk, John, Scott, R., Moscato, P., Milward, E.
Format:	Journal Article
Published:	Elsevier 2012
Subjects:	Microarray Mouse model HFE Hemochromatosis Iron
Online Access:	http://hdl.handle.net/20.500.11937/40786

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