Brain transcriptome perturbations in the Hfe -/- mouse model of genetic iron loading
Severe disruption of brain iron homeostasis can cause fatal neurodegenerative disease, however debate surrounds the neurologic effects of milder, more common iron loading disorders such as hereditary hemochromatosis, which is usually caused by loss-of-function polymorphisms in the HFE gene. There is...
| Main Authors: | , , , , , , , , |
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| Format: | Journal Article |
| Published: |
Elsevier
2012
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| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.11937/40786 |