Effect of co-solvent addition on the reaction kinetics of the lipase-catalyzed resolution of ibuprofen ester

BACKGROUND: The addition of co-solvent is not limited to enhancing the catalytic rate, it could also assist in situ racemization in the dynamic kinetic resolution of racemic compounds by increasing the reactivity of the base catalyst employed. In the current work, reaction media with the presence of...

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Bibliographic Details
Main Authors: Gonawan, Fadzil, Lau, John, Kamaruddin, Azlina, Uzir, Mohamad
Format: Journal Article
Published: Wiley 2013
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/40728