Polymorphisms and interspecies differences of the activating and inhibitory Fc?RII of Macaca nemestrina influence the binding of human IgG subclasses

Little is known of the impact of Fc receptor (FcR) polymorphism in macaques on the binding of human (hu)IgG, and nothing is known of this interaction in the pig-tailed macaque (Macaca nemestrina), which is used in preclinical evaluation of vaccines and therapeutic Abs. We defined the sequence and hu...

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Bibliographic Details
Main Authors: Trist, H., Tan, P., Wines, B., Ramsland, Paul, Orlowski, E., Stubbs, J., Gardiner, E., Pietersz, G., Kent, S., Stratov, I., Burton, D., Hogarth, P.
Format: Journal Article
Published: 2014
Online Access:http://hdl.handle.net/20.500.11937/40404