Star-Shaped Amphiphilic Hyperbranched Polyglycerol Conjugated with Dendritic Poly(l-lysine) for the Codelivery of Docetaxel and MMP-9 siRNA in Cancer Therapy.

The drug/gene codelivery is a promising strategy for cancer treatment. Herein, to realize the codelivery of docetaxel and MMP-9 siRNA plasmid efficiently into tumor cells, a star-shaped amphiphilic copolymer consisting of hyperbranched polyglycerol derivative (HPG-C18) and dendritic poly(l-lysine) (...

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Bibliographic Details
Main Authors: Zhou, X., Zheng, Q., Wang, C., Xu, J., Wu, Jian-Ping, Kirk, Brett, Ma, D., Xue, W.
Format: Journal Article
Published: American Chemical Society 2016
Online Access:http://hdl.handle.net/20.500.11937/40344