Gelsolin induces colorectal tumor cell invasion via modulation of the urokinase-type plasminogen activator cascade

Gelsolin is a cytoskeletal protein which participates in actin filament dynamics and promotes cell motility and plasticity. Although initially regarded as a tumor suppressor, gelsolin expression in certain tumors correlates with poor prognosis and therapy-resistance. In vitro, gelsolin has anti-apop...

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Bibliographic Details
Main Authors: Zhuo, J., Tan, E., Yan, B., Tochhawng, L., Jayapal, M., Koh, S., Tay, H., Maciver, S., Hooi, S., Salto-Tellez, M., Kumar, Alan Prem, Goh, Y., Lim, Y., Yap, C.
Format: Journal Article
Published: Public Library of Science 2012
Online Access:http://hdl.handle.net/20.500.11937/40322