Potential role of signal transducer and activator of transcription (STAT)3 signaling pathway in inflammation, survival, proliferation and invasion of hepatocellular carcinoma

Potential role of signal transducer and activator of transcription (STAT)3 signaling pathway in inflammation, survival, proliferation and invasion of hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is one of the most lethal malignancies, and is also the fourth most common cancer worldwide with around 700,000 new cases each year. Currently, first line chemotherapeutic drugs used for HCC include fluorouracil, cisplatin, doxorubicin, paclitaxel and mitomycin, but mo...

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Bibliographic Details
Main Authors: Subramaniam, A., Shanmugam, M., Perumal, E., Li, F., Nachiyappan, A., Dai, X., Swamy, S., Anh, K., Kumar, Alan Prem, Tan, B., Hui, K., Sethi, G.
Format: Journal Article
Published: Elsevier 2012
Subjects:
proliferation
apoptosis
invasion
STAT3
hepatocellular carcinoma
JAKs
Online Access:http://hdl.handle.net/20.500.11937/3994

Internet

http://hdl.handle.net/20.500.11937/3994

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