Tumour-promoting activity of altered WWPI expression in breast cancer and its utility as a prognostic indicator

WWP1 is a ubiquitin ligase, associated with the post-translational regulation of several tumour-promoting and tumour suppressor proteins. Here we show that WWP1 expression is up-regulated in a subset of breast tumour cell lines and primary breast tumours. We overexpressed WWP1 in MCF10A breast epith...

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Bibliographic Details
Main Authors: Huu, N., Ryder, W., Zeps, Nikolajs, Flasza, M., Chiu, M., Hanby, A., Poulsom, R., Clarke, R., Baron, M.
Format: Journal Article
Published: John Wiley & Sons Ltd 2008
Online Access:http://hdl.handle.net/20.500.11937/39791